Metabolomics detection is one of the significant demands in the fundamental research of life sciences and clinical medicine. Surface-Enhanced Raman Spectroscopy (SERS) is advancing metabolomics with its high sensitivity and specificity, providing a non-invasive and rapid alternative to traditional metabolite analysis methods. This talk explores SERS's utility in metabolite phenotyping and quantification, showcasing its capabilities in detecting cancer biomarkers and offering insights into disease metabolism. The introduction of the "SERSome" technique and digital colloid-enhanced Raman spectroscopy (dCERS) addresses the challenge of signal heterogeneity, enhancing SERS's reproducibility and accuracy. SERS's potential extends to single-cell analysis, multi-omics integration, and therapeutic drug monitoring, positioning it as a promising tool in metabolomics research and clinical diagnostics.  

Speaker

 Prof. Jian Ye

School of Biomedical Engineering, SJTU

Time

 2024.11.27 12:00-13:30