Speaker

Bin Li

Time

2025.11.12 16:00-17:30

Abstract

Research in our laboratory mainly focuses on understanding molecular mechanism underlying the functional instability, and imbalance of FOXP3+ Regulatory T cells (Treg) and RORγt+ T helper 17 cells (Th17) in inflammatory diseases, as well as their therapeutically modulation, especially by compounds from Chinese Traditional Medicine. By using and developing Treg specifically depletion animal models, as well as these state-of-art cutting-edge technologies in single cell sequencing and immune cell metabolism, we are revealing the functional role of tissue-specific Treg subsets and mechanisms underlying their perturbation in health and disease settings. We expect that our original findings will be translational to biomedical industry and be beneficial to the future of Treg-based immunotherapy.

Bio

Bin Li, Ph.D. Yu He Scholar; Distinguished Professor of SJTUSenior Investigator & Associate Director, Shanghai Institute of Immunology, Adjunct “Guangci” Professor, Shanghai Ruijin Hospital, Shanghai Jiao Tong University School of Medicine, Shanghai Jiao Tong University.